John Ambrose, MD, FACC

Professor of Clinical Medicine
Cardiology - Fresno
+1 559 459-3872

John Ambrose, MD
Professor
Program Director,
Cardiovascular Fellowship
UCSF Fresno

Dr. John Ambrose is an internationally renowned expert in coronary artery disease and is one of the great pioneers in acute coronary syndromes. He has published extensively and his work has laid the foundation for the current theories on unstable angina, myocardial infarction and the vulnerable plaque, among others. Before coming to Fresno, Dr. Ambrose was the Director of the Cardiovascular Center at Saint Vincent Catholic Medical Centers in Manhattan. Before that, he was the Director of Cardiac Catheterization at Mount Sinai Medical Center in New York. He has been included in every edition of “Best Doctors in America.” Dr. Ambrose sang professionally in New York and continues to sing with his wife with the Fresno Grand Opera.

Publications: 

Time to Tweak the Definition of Type 2 Myocardial Infarction.

The American journal of cardiology

Ambrose JA, Kiel R, AlBayati A

ARTIFICIAL INTELLIGENCE and THE DOCTOR-PATIENT RELATIONSHIP: Category: Commentary.

The American journal of medicine

Kingsford PA, Ambrose JA

Identifying and Treating Vulnerable Atherosclerotic Plaques.

The American journal of cardiology

Ambrose JA, Sharma AV

New Precordial T Wave Inversions in Hospitalized Patients.

The American journal of medicine

Thinda N, Ambrose JA, Bhullar A, Huang S, Asadourian M, Sadhale A, Chua RA, Wessel R

The Reply.

The American journal of medicine

Ambrose JA

The Look Inside: Is it Clinically Relevant?

JACC. Cardiovascular imaging

Ambrose JA, Poosti K

Reducing Tobacco-Related Morbidity and Mortality-A Call to Action.

JAMA cardiology

Ambrose JA, Najafi A, Barua R

Reducing Tobacco-Related Disability in Chronic Smokers.

The American journal of medicine

Ambrose JA, Najafi A, Jain V, Muller JE, Ranka S, Barua RS

Anatomic or functional testing in stable patients with suspected CAD: contemporary role of cardiac CT in the ISCHEMIA trial era.

The international journal of cardiovascular imaging

Rodriguez-Granillo GA, Nieman K, Carrascosa P, Campisi R, Ambrose JA

Misdiagnosis of Type II Myocardial Infarction.

Journal of the American College of Cardiology

Saleh MA, Ambrose JA, Poosti K, Rajyaguru C, Sargsyan M, Najafi A, Bhullar A, Sandhu U, Hashmi M, Sandhu C

Environmental Tobacco Smoke and Cardiovascular Disease.

International journal of environmental research and public health

DiGiacomo SI, Jazayeri MA, Barua RS, Ambrose JA

Understanding myocardial infarction.

F1000Research

Saleh M, Ambrose JA

In-Hospital Outcomes of Percutaneous Coronary Intervention in America's Safety Net: Insights From the NCDR Cath-PCI Registry.

JACC. Cardiovascular interventions

Acharya T, Salisbury AC, Spertus JA, Kennedy KF, Bhullar A, Reddy HKK, Joshi BK, Ambrose JA

Normalization of Testosterone Levels After Testosterone Replacement Therapy Is Not Associated With Reduced Myocardial Infarction in Smokers.

Mayo Clinic proceedings. Innovations, quality & outcomes

Oni OA, Sharma R, Chen G, Sharma M, Gupta K, Dawn B, Sharma R, Parashara D, Savin VJ, Cherian G, Ambrose JA, Barua RS

Normalization of Testosterone Levels After Testosterone Replacement Therapy Is Associated With Decreased Incidence of Atrial Fibrillation.

Journal of the American Heart Association

Sharma R, Oni OA, Gupta K, Sharma M, Sharma R, Singh V, Parashara D, Kamalakar S, Dawn B, Chen G, Ambrose JA, Barua RS

Finding the High-Risk Patient in Primary Prevention Is Not as Easy as a Conventional Risk Score!

The American journal of medicine

Ambrose JA, Acharya T, Roberts MJ

Left Atrial Area and Right Ventricle Dimensions in Non-gated Axial Chest CT can Differentiate Pulmonary Hypertension Due to Left Heart Disease from Other Causes.

Journal of cardiovascular computed tomography

Katikireddy CK, Singh M, Muhyieddeen K, Acharya T, Ambrose JA, Samim A

Normalization of testosterone level is associated with reduced incidence of myocardial infarction and mortality in men.

European heart journal

Sharma R, Oni OA, Gupta K, Chen G, Sharma M, Dawn B, Sharma R, Parashara D, Savin VJ, Ambrose JA, Barua RS

A Single Controlled Exposure to Secondhand Smoke May Not Alter Thrombogenesis or Trigger Platelet Activation.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Srikanth S, Sy F, Kotak K, Kiel RG, Bajwa M, Tandon A, Loures-Vale AA, Aftab W, Tringali S, Ambrose JA

Reducing acute coronary events: the solution is not so difficult!

The American journal of medicine

Ambrose JA, Acharya T

Femoral micropuncture or routine introducer study (FEMORIS).

Cardiology

Ambrose JA, Lardizabal J, Mouanoutoua M, Buhari CF, Berg R, Joshi B, El-Sherief K, Wessel R, Singh M, Kiel R

Are the culprit lesions severely stenotic?

JACC. Cardiovascular imaging

Niccoli G, Stefanini GG, Capodanno D, Crea F, Ambrose JA, Berg R

Frequency of Takotsubo cardiomyopathy in postmenopausal women presenting with an acute coronary syndrome.

The American journal of cardiology

Sy F, Basraon J, Zheng H, Singh M, Richina J, Ambrose JA

Mechanisms of coronary thrombosis in cigarette smoke exposure.

Arteriosclerosis, thrombosis, and vascular biology

Barua RS, Ambrose JA

Managing coronary thrombus in the cath lab during PCI.

Current cardiology reviews

Ambrose JA

Angiographic correlates in type 1 and 2 MI by the universal definition.

JACC. Cardiovascular imaging

Ambrose JA, Loures-Vale A, Javed U, Buhari CF, Aftab W

Acute myocardial infarction and the five-chambered heart.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Lardizabal JA, Javed U, Ambrose JA

Acute cigarette smoke exposure reduces clot lysis--association between altered fibrin architecture and the response to t-PA.

Thrombosis research

Barua RS, Sy F, Srikanth S, Huang G, Javed U, Buhari C, Margosan D, Aftab W, Ambrose JA

Evaluation of plaque composition by intravascular ultrasound "virtual histology": the impact of dense calcium on the measurement of necrotic tissue.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Sales FJ, Falcão BA, Falcão JL, Ribeiro EE, Perin MA, Horta PE, Spadaro AG, Ambrose JA, Martinez EE, Furuie SS, Lemos PA

Vulnerable plaques and patients: improving prediction of future coronary events.

The American journal of medicine

Ambrose JA, Srikanth S

Effects of cigarette smoke exposure on clot dynamics and fibrin structure: an ex vivo investigation.

Arteriosclerosis, thrombosis, and vascular biology

Barua RS, Sy F, Srikanth S, Huang G, Javed U, Buhari C, Margosan D, Ambrose JA

Frequency of elevated troponin I and diagnosis of acute myocardial infarction.

The American journal of cardiology

Javed U, Aftab W, Ambrose JA, Wessel RJ, Mouanoutoua M, Huang G, Barua RS, Weilert M, Sy F, Thatai D

The editor's roundtable: the vulnerable plaque.

The American journal of cardiology

Friedewald VE, Ambrose JA, Stone GW, Roberts WC, Willerson JT

Human myocardium preconditioning during successive balloon inflations: irrelevant influence of both collateral recruitment and clinical pre-intervention interference.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Pimentel WA, Martinez EE, Ambrose JA, Mathias W, Arruda A, Horta PE, Ribeiro EE, Esteves A, Lemos PA, Ramires JA

Myocardial perfusion scintigraphy to predict outcomes after coronary stenting.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Zalc S, Ambrose JA, Lemos PA, Ribeiro EE, Soares J, Giorgi MC, Esteves-Filho A, Horta PE, Meneghetti JC, Ramires JA, Martinez EE

Myocardial ischemia and infarction.

Journal of the American College of Cardiology

Ambrose JA

Impact of completeness of percutaneous coronary intervention revascularization on long-term outcomes in the stent era.

Circulation

Hannan EL, Racz M, Holmes DR, King SB, Walford G, Ambrose JA, Sharma S, Katz S, Clark LT, Jones RH

A risk score to predict in-hospital mortality for percutaneous coronary interventions.

Journal of the American College of Cardiology

Wu C, Hannan EL, Walford G, Ambrose JA, Holmes DR, King SB, Clark LT, Katz S, Sharma S, Jones RH

Sirolimus- and taxol-eluting stents differ towards intimal hyperplasia and re-endothelialization.

The Journal of invasive cardiology

Liuzzo JP, Ambrose JA, Coppola JT

Early prognostic usefulness of C-reactive protein added to the Thrombolysis In Myocardial Infarction risk score in acute coronary syndromes.

The American journal of cardiology

Foussas SG, Zairis MN, Lyras AG, Patsourakos NG, Tsirimpis VG, Katsaros K, Beldekos DJ, Handanis SM, Mytas DZ, Karidis KS, Tselioti PG, Prekates AA, Ambrose JA

Volume-outcome relationships for percutaneous coronary interventions in the stent era.

Circulation

Hannan EL, Wu C, Walford G, King SB, Holmes DR, Ambrose JA, Sharma S, Katz S, Clark LT, Jones RH

Triple valve repair for rheumatic heart disease.

Journal of cardiac surgery

Liuzzo JP, Shin YT, Lucariello R, Klapholz M, Lang SJ, Braff R, Guan H, Coppola JT, Ambrose JA

Plaque rupture and intracoronary thrombus in nonculprit vessels: an eyewitness account.

Journal of the American College of Cardiology

Ambrose JA, D'Agate DJ

Preprocedural plasma C-reactive protein levels, postprocedural creatine kinase-MB release, and long-term prognosis after successful coronary stenting (four-year results from the GENERATION study).

The American journal of cardiology

Zairis MN, Ambrose JA, Ampartzidou O, Lyras AG, Manousakis SJ, Makrygiannis SS, Beldekos DJ, Devoe MC, Fakiolas CN, Prekates AA, Olympios CD, Argyrakis SK, Foussas SG, GENERATION Study Group

The pathophysiology of cigarette smoking and cardiovascular disease: an update.

Journal of the American College of Cardiology

Ambrose JA, Barua RS

Predictors of troponin elevation after percutaneous coronary intervention.

The American journal of cardiology

Mandadi VR, DeVoe MC, Ambrose JA, Prakash AM, Varshneya N, Gould RB, Nguyen TH, Geagea JP, Radojevic JA, Sehhat K, Barua RS

Luminal recovery from six to twelve months after implantation of "thicker strut" coronary stents.

The American journal of cardiology

Meireles GC, Lemos PA, Ambrose JA, Ribeiro E, Horta PE, Perin M, Ramires JA, Martinez EE

Pilot study of oral rapamycin to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial).

The Journal of invasive cardiology

Rodriguez AE, Alemparte MR, Vigo CF, Pereira CF, Llaurado C, Russo M, Virmani R, Ambrose JA

Identification of vulnerable atherosclerotic plaques.

Expert review of cardiovascular therapy

Staniloae CS, Ambrose JA

Frequency of and outcome of acute coronary syndromes in patients with human immunodeficiency virus infection.

The American journal of cardiology

Ambrose JA, Gould RB, Kurian DC, DeVoe MC, Pearlstein NB, Coppola JT, Siegal FP

C-reactive protein and ST-segment monitoring by continuous 12-lead electrocardiogram in patients with primary unstable angina pectoris.

The American journal of cardiology

Zairis MN, Ambrose JA, Papadaki OA, Manousakis SJ, Stefanidis AS, DeVoe MC, Handanis SM, Olympios CD, Foussas SG

Peripheral conduction disease in left ventricular dysfunction.

The American journal of cardiology

Puttappa R, Raia F, Bhat S, Braff R, Mandadi VR, Barua RS, DeVoe MC, Boal BH, Ambrose JA

The impact of plasma levels of C-reactive protein, lipoprotein (a) and homocysteine on the long-term prognosis after successful coronary stenting: The Global Evaluation of New Events and Restenosis After Stent Implantation Study.

Journal of the American College of Cardiology

Zairis MN, Ambrose JA, Manousakis SJ, Stefanidis AS, Papadaki OA, Bilianou HI, DeVoe MC, Fakiolas CN, Pissimissis EG, Olympios CD, Foussas SG, Global Evaluation of New Events and Restenosis After Stent Implantation Study Group

Acute coronary lesions and troponin elevation in unstable angina pectoris or non-ST elevation acute myocardial infarction.

The American journal of cardiology

Ambrose JA, Gould RB, Zairis MN, DeVoe MC, Nguyen TH, Geagea JP, Arias JH, Prakash AM, Varshneya N, Meraj P, Barua RS

Heavy and light cigarette smokers have similar dysfunction of endothelial vasoregulatory activity: an in vivo and in vitro correlation.

Journal of the American College of Cardiology

Barua RS, Ambrose JA, Eales-Reynolds LJ, DeVoe MC, Zervas JG, Saha DC

A new paradigm for plaque stabilization.

Circulation

Ambrose JA, Martinez EE

Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction.

Current treatment options in cardiovascular medicine

Ambrose JA, Tai Z